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Bases estructurales de la latencia en el inhibidor-1 del activador del plasminógeno

J Mottonen1, A Strand, J Symersky

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235-9050.

Nature
|January 16, 1992
PubMed
Resumen

El inhibidor-1 del activador del plasminógeno humano (PAI-1) adopta un estado inactivo estable y latente sin escisión. Esta estructura se asemeja a las serpientes escindidas, lo que sugiere mecanismos de estabilidad compartidos.

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