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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Video Experimental Relacionado

Updated: Jun 7, 2026

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
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Paramutation: desde el maíz a los ratones.

Vicki L Chandler1

  • 1BIO5 Institute and Department of Plant Sciences, University of Arizona, Tucson, AZ 85721, USA. chandler@ag.arizona.edu

Cell
|February 27, 2007
PubMed
Resumen
Este resumen es generado por máquina.

La paramutation epigenetically transfiere la información de la expresión génica entre alelos, estableciendo estados heredables a través de generaciones. Las moléculas de ARN son mediadores clave de este proceso en el maíz y los ratones.

Área de la Ciencia:

  • La epigenética es la epigenética.
  • Biología Molecular Biología Molecular
  • Genética La genética.

Sus antecedentes:

  • La paramutación es un proceso epigenético único en el que el estado de expresión de un alelo se copia en otro alelo.

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  • Este proceso da como resultado un cambio hereditario en la expresión génica sin alterar la secuencia de ADN subyacente.