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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Múltiples funciones de la quinasa relacionada con IKK IKKepsilon en la inmunidad antiviral mediada por interferón

Benjamin R Tenoever1, Sze-Ling Ng, Mark A Chua

  • 1Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.

Science (New York, N.Y.)
|March 3, 2007
PubMed
Resumen

IKKepsilon es crucial para la defensa antiviral. Los ratones que carecen de IKKepsilon son susceptibles a las infecciones virales debido a una vía de señalización de interferón defectuosa que afecta la activación génica.

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