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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 19, 2013

Patrones de mutación somática en los genomas de cáncer humano

Christopher Greenman1, Philip Stephens, Raffaella Smith

  • 1Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Nature
|March 9, 2007
PubMed
Resumen

Los investigadores secuenciaron los genomas del cáncer, identificando más de 1.000 mutaciones en los genes de la proteína quinasa. Este estudio implica aproximadamente 120 genes conductores, expandiendo el repertorio conocido de genes del cáncer.

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