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Videos de Conceptos Relacionados

Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Hematopoiesis01:21

Hematopoiesis

The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Production of Formed Elements01:34

Production of Formed Elements

Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
Most HSCs commit to...

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Video Experimental Relacionado

Updated: Jun 17, 2026

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
12:03

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors

Published on: July 8, 2012

De la célula madre al progenitor y viceversa.

András Simon1, Jonas Frisén

  • 1Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77 Stockholm, Sweden.

Cell
|March 14, 2007
PubMed
Resumen

Las células progenitoras amplificadoras de tránsito pueden reemplazar las células madre de los tejidos perdidos. Este hallazgo arroja luz sobre la regeneración de las células madre y la homeostasis tisular.

Área de la Ciencia:

  • Biología del desarrollo Biología del desarrollo.
  • Biología de las células madre Biología de las células madre
  • Regeneración celular y regeneración celular.

Sus antecedentes:

  • Las células madre del tejido mantienen la homeostasis del tejido a través de la auto-renovación y la diferenciación.
  • El destino de las células madre tras la pérdida es una cuestión crítica en la biología regenerativa.

Objetivo del estudio:

  • Investigar el potencial de la progenie de células madre para reemplazar las células madre perdidas.
  • Comprender los mecanismos de regeneración de tejidos y mantenimiento de las células madre.

Principales métodos:

  • El estudio propone un modelo basado en la literatura existente y consideraciones teóricas.
  • No se detalló ningún método experimental específico en el resumen proporcionado.

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Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells
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Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells

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Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells
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Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells

Published on: November 1, 2017

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Last Updated: Jun 17, 2026

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
12:03

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors

Published on: July 8, 2012

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells
08:00

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells

Published on: January 12, 2015

Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells
14:37

Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells

Published on: November 1, 2017

Principales resultados:

  • Se propone que las células progenitoras amplificadoras de tránsito, la progenie de las células madre, tengan la capacidad de reemplazar las células madre perdidas.
  • Este mecanismo de reemplazo podría ser crucial para mantener la integridad del tejido.

Conclusiones:

  • La pérdida de células madre puede ser compensada por su descendencia diferenciada.
  • Esto pone de relieve una potencial capacidad regenerativa dentro de las poblaciones de células progenitoras.