Video Experimental Relacionado

Updated: Jul 16, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

El ARN no codificante XIST funciona independientemente del BRCA1 en la inactivación X

Cuiying Xiao1, Judith A Sharp, Misako Kawahara

  • 1Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, 10/9N105, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|March 14, 2007
PubMed
Resumen

Las mutaciones en BRCA1 aumentan el riesgo de cáncer. Sin embargo, este estudio encontró que BRCA1 no regula la localización del ARN XIST o la expresión génica en el cromosoma X inactivo, lo que desafía los modelos anteriores.

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