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Updated: May 8, 2026
08:53
Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
Published on: February 18, 2011
Otras pruebas de la comunicación de BRCA1 con el cromosoma X inactivo
Daniel P Silver1, Stoil D Dimitrov, Jean Feunteun
1Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Cell
|March 14, 2007
Resumen
El gen BRCA1, un supresor del cáncer de mama y de ovario, juega un papel en la regulación del cromosoma X inactivo (Xi). Una nueva investigación apoya el BRCA1
Área de la Ciencia:
- * Biología molecular.
- * Genética del cáncer.
- * Epigenética y regulación génica.
Sus antecedentes:
- * BRCA1 es un gen supresor de tumores conocido involucrado en la reparación del ADN y el control del punto de control del ciclo celular.
- * Estudios previos sugirieron una posible interacción entre BRCA1 y el cromosoma X inactivo (Xi) en células femeninas.
- * Investigaciones recientes han puesto en duda esta interacción, lo que requiere una mayor investigación.
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X-chromosome...
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