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Updated: Jul 12, 2026

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Estructura e interacción en soluciones acuosas de urea-trimetilamina-N-óxido

Sandip Paul1, Grenfell N Patey

  • 1Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.

Journal of the American Chemical Society
|March 22, 2007
PubMed
Resumen

El Trimetilamina-N-óxido (TMAO) estabiliza las estructuras de las proteínas al interactuar favorablemente con el agua y la urea. Esto sugiere que el TMAO inhibe el despliegue de proteínas al ser preferentemente solvado, protegiendo así a las proteínas de los efectos desnaturalizantes de la urea.

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