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Metabolic Pathway Confirmation and Discovery Through 13C-labeling of Proteinogenic Amino Acids
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Published on: January 26, 2012

Potencialmente amiloidogénicos, derivados carboxilo-terminales del precursor de la proteína amiloide

S Estus1, T E Golde, T Kunishita

  • 1Division of Neuropathology, Case Western Reserve University, Cleveland, OH 44106.

Science (New York, N.Y.)
|February 7, 1992
PubMed
Resumen

La enfermedad de Alzheimer implica la deposición de la proteína beta amiloide (beta AP). La investigación muestra que el procesamiento de beta APP produce derivados carboxilo-terminales, con dos grandes que probablemente forman la proteína beta amiloide en el cerebro.

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