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Prevención secundaria del accidente cerebrovascular y del ataque isquémico transitorio: ¿es la respuesta más
1Cardiovascular Division, Department of Medicine, Brigham & Women's Hospital, 65 Landsdowne St, Rm 275, Cambridge, MA 02139, USA. jliao@rics.bwh.harvard.edu
Circulation
|March 29, 2007
Resumen
La prevención secundaria del accidente cerebrovascular es crucial, ya que la terapia antiplaquetaria dual para afecciones cardíacas no previene los accidentes cerebrovasculares recurrentes. Las terapias combinadas ofrecen una inhibición plaquetaria óptima para la protección secundaria del accidente cerebrovascular.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- Medicina Cardiovascular La medicina cardiovascular es una especialidad de la salud.
- Farmacología Farmacología.
Sus antecedentes:
- Los eventos cerebrovasculares recurrentes representan una parte significativa de los accidentes cerebrovasculares anuales en los Estados Unidos.
- La prevención del accidente cerebrovascular secundario es un objetivo de gestión clave para los pacientes con antecedentes de accidente cerebrovascular o ataque isquémico transitorio (AIT).
Objetivo del estudio:
- Evaluar la eficacia y seguridad de las terapias antiplaquetarias para la prevención secundaria del ictus.
- Para determinar las estrategias antiplaquetarias óptimas para pacientes con accidente cerebrovascular isquémico.
Principales métodos:
- Revisión de ensayos clínicos recientes sobre el tratamiento antiplaquetario en pacientes con accidente cerebrovascular.
- Comparación de la eficacia antiplaquetaria en enfermedades cerebrovasculares frente a enfermedades cardiovasculares.
Principales resultados:
- La doble terapia antiplaquetaria beneficiosa para los síndromes coronarios no proporciona protección secundaria contra el accidente cerebrovascular.
- Los pacientes con accidente cerebrovascular pueden requerir diferentes regímenes antiplaquetarios debido a distintas etiologías y riesgos de sangrado.
- La inhibición plaquetaria óptima para la prevención del accidente cerebrovascular implica un equilibrio para evitar el aumento del sangrado.
Conclusiones:
- Las terapias antiplaquetarias para el accidente cerebrovascular isquémico deben priorizar la protección del accidente cerebrovascular secundario sobre la protección del miocardio.
- Las terapias combinadas pueden ofrecer la mejor estrategia para la protección secundaria del accidente cerebrovascular al optimizar la inhibición plaquetaria y la protección vascular.
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