Video Experimental Relacionado
Updated: May 5, 2026
07:09
A Rapid and Efficient Method for Assessing Pathogenicity of Ustilago maydis on Maize and Teosinte Lines
Published on: January 4, 2014
8.0K
Un sistema regulatorio de dos componentes para el auto-/no auto-reconocimiento en Ustilago puede deshacerse
B Gillissen1, J Bergemann, C Sandmann
1Institut für Genbiologische Forschung Berlin GmbH, Federal Republic of Germany.
Cell
|February 21, 1992
Resumen
Los investigadores descubrieron un segundo gen regulador, bW, en el locus maydis b de EE.UU., junto con el conocido gen bE. La interacción de los productos genéticos bE y bW es clave para el desarrollo de hongos.
Área de la Ciencia:
- La micología de la micología.
- Genética La genética.
- Biología Molecular Biología Molecular
Sus antecedentes:
- El locus b multialélico en Ustilago maydis regula el desarrollo sexual y patógeno.
- Anteriormente se había identificado un solo gen regulador en el locus b, con su producto polipéptido interactuando para controlar el desarrollo sexual.
Objetivo del estudio:
- Investigar la base genética del desarrollo sexual y patógeno en Ustilago maydis.
- Para identificar genes reguladores adicionales dentro del locus b.
Principales métodos:
- El análisis genético de la U. maydis b locus.
- Análisis bioinformático de secuencias de genes y dominios de proteínas.
Principales resultados:
- Identificación de un segundo gen regulador en el locus b, llamado bW, distinto del gen bE previamente identificado.
- Los genes bE y bW existen en múltiples alelos y comparten estructuras organizativas similares.
- Los productos genéticos (polipeptídeos) exhiben variabilidad N-terminal específica del alelo y dominios C-terminal conservados con un motivo relacionado con el homeodominio.
- La evidencia genética confirma que la interacción entre los polipéptidos bE y bW de diferentes alelos es crucial para el control regulatorio.
Conclusiones:
- El U. maydis b locus contiene al menos dos genes reguladores, bE y bW.
- La interacción entre los polipéptidos alelo-específicos bE y bW es el principal mecanismo regulador para el desarrollo sexual en U. maydis.
Videos de Conceptos Relacionados
01:28Yeast Signaling
15.7K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
15.7K
01:28Global Regulatory Systems
961
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
961
01:28Gene Regulation in Microbial Communities: Quorum Sensing
960
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
960
01:17Gene Regulation During Sporulation
719
Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
719
01:30Other Stress Responses in Bacteria
593
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
593
01:28Regulation of Bacterial Virulence
80
Pathogenic bacteria employ a range of regulatory mechanisms to modulate the expression of virulence genes in response to environmental and host-derived signals. These mechanisms ensure that virulence factors are expressed only under favorable conditions, thereby optimizing infection and survival strategies.Mechanisms of Virulence RegulationKey regulatory strategies include:Two-Component Systems: These consist of a membrane-bound sensor kinase and a cytoplasmic response regulator. Environmental...
80