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Updated: Jul 14, 2026
09:39
Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes
Published on: December 20, 2014
Comentario sobre "Un papel independiente del centrosoma para las proteínas gamma-TuRC en el punto de control de
Beth A A Weaver1, Don W Cleveland
1Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0670, USA.
Science (New York, N.Y.)
|May 19, 2007
Resumen
El estudio sugiere que la nucleación de microtúbulos no es esencial para la señalización del punto de control mitótico. Las observaciones se alinean con las vías establecidas que involucran las interacciones cinetocoro-microtubulares, no los efectos de agotamiento del complejo de anillos gamma-tubulina.
Área de la Ciencia:
- Biología celular Biología celular.
- Biología Molecular Biología Molecular
- Genética La genética.
Sus antecedentes:
- La nucleación de microtúbulos es crucial para la división celular.
- El complejo de anillos de gamma-tubulina (gamma-TuRC) es un componente clave en la nucleación de microtúbulos.
- La señalización del punto de control mitótico asegura una segregación cromosómica precisa.
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