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Videos de Conceptos Relacionados

Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Histone Modification02:32

Histone Modification

The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying DNA...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

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Video Experimental Relacionado

Updated: May 7, 2026

Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

Las percepciones de la epigenética.

Adrian Bird1

  • 1Wellcome Trust Centre for Cell Biology, Edinburgh University, The King's Buildings, Edinburgh EH9 3JR, UK.

Nature
|May 25, 2007
PubMed
Resumen

La epigenética explora cómo se altera la función génica sin cambiar la secuencia del ADN. Este emocionante campo ofrece nuevos conocimientos sobre la biología más allá del determinismo genético.

Área de la Ciencia:

  • Biología Biología Biología.
  • Genética La genética.
  • La epigenética es la epigenética.

Sus antecedentes:

  • El estudio de los genes está bien establecido, pero el concepto de 'epígenos' sigue siendo elusivo.
  • La epigenética ha ganado una atención significativa, con más de 2.500 artículos y reuniones científicas dedicadas en el último año.
  • Se presenta como una ciencia revolucionaria, desafiando la noción de determinismo genético.

Objetivo del estudio:

  • Para definir y explicar el campo emergente de la epigenética.
  • Aclarar el alcance y la importancia de la investigación epigenética en la biología contemporánea.

Principales métodos:

  • Este resumen no detalla los métodos específicos.
  • El campo se basa en varias técnicas de biología molecular para estudiar la regulación génica.

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Pattern-based Search of Epigenomic Data Using GeNemo
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Pattern-based Search of Epigenomic Data Using GeNemo

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An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

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Videos de Experimentos Relacionados

Last Updated: May 7, 2026

Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

Principales resultados:

  • El resumen destaca el rápido crecimiento y el interés popular en la epigenética.
  • Hace hincapié en la epigenética como un campo dinámico que ofrece alternativas a las explicaciones puramente genéticas.

Conclusiones:

  • La epigenética representa un área significativa y en rápida evolución del estudio biológico.
  • Proporciona un marco para la comprensión de la complejidad biológica más allá de la secuencia de ADN.