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La IL-21 inicia una vía alternativa para inducir las células proinflamatorias T(H) 17

Thomas Korn1, Estelle Bettelli1, Wenda Gao2

  • 1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|June 22, 2007
PubMed
Resumen

La interleucina-6 (IL-6) es crucial para la diferenciación de las células T ayudantes 17 (T (((H) 17). En los ratones con deficiencia de IL-6, las células T (Treg) reguladoras dominan, pero la IL-21 puede inducir a las células T ((H) 17), revelando vías alternativas.

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