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Updated: Jul 13, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Anulación C-2/c-3 y alquilación C-2 de los indolos con ésteres de 2-alcoxiciclopropanoato

Barbora Bajtos1, Ming Yu, Hongda Zhao

  • 1Department of Chemistry, The University of Western Ontario, London, Ontario, N6A 1Y2, Canada.

Journal of the American Chemical Society
|July 17, 2007
PubMed
Resumen

Este estudio detalla una reacción de anulación de indol con ciclopropanatos, logrando una alta eficiencia y control estereoquímico. El proceso selectivamente forma múltiples estereocentros y ofrece una nueva ruta a los indoles C-2 alquilados.

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