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Updated: Jul 13, 2026
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
El manejo actual y futuro de la psoriasis
Alan Menter1, Christopher Em Griffiths2
1Baylor Research Institute and Southwestern Medical School, Dallas, Texas, 75246, USA.
Lancet (London, England)
|July 31, 2007
Resumen
El manejo efectivo de la psoriasis requiere evaluar la extensión de la enfermedad y considerar la calidad de vida. Un enfoque basado en la evidencia guía la selección del tratamiento, desde agentes tópicos hasta terapias biológicas avanzadas para la psoriasis grave.
Área de la Ciencia:
- Dermatología e Inmunología.
- La medicina basada en la evidencia.
Sus antecedentes:
- El manejo de la psoriasis requiere evaluar la gravedad de la enfermedad y los factores específicos del paciente.
- Un enfoque holístico que aborde la discapacidad psicosocial y la calidad de vida es crucial.
- Las ubicaciones específicas de la enfermedad (palmas, plantas, cara, uñas) y la artritis psoriásica influyen en las opciones de tratamiento.
Objetivo del estudio:
- Para esbozar las actuales estrategias de tratamiento basadas en la evidencia para la psoriasis.
- Para resaltar la evolución de las terapias de la psoriasis, incluyendo nuevos agentes biológicos.
- Para enfatizar la necesidad de un plan de tratamiento integral e individualizado.
Principales métodos:
- Revisión de las opciones terapéuticas actuales para la psoriasis.
- Análisis de la evidencia que apoya las diferentes modalidades de tratamiento.
- La consideración de la extensión de la enfermedad, la ubicación y las comorbilidades del paciente.
Principales resultados:
- Los agentes tópicos son primarios para la psoriasis leve y las lesiones recalcitrantes.
- La fototerapia se adapta a enfermedades moderadas.
- Las terapias sistémicas, incluida la fotoquimioterapia, los agentes orales y los biológicos, son vitales para la psoriasis grave, con los biológicos revolucionando la atención.
Conclusiones:
- Un enfoque holístico basado en la evidencia es esencial para el manejo óptimo de la psoriasis.
- Los tratamientos actuales van desde agentes tópicos hasta terapias sistémicas y biológicas avanzadas.
- La investigación en curso tiene como objetivo desarrollar estrategias seguras y a largo plazo de control de la psoriasis.
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