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Updated: May 7, 2026

Selective Capture of 5-hydroxymethylcytosine from Genomic DNA
06:26

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Published on: October 5, 2012

Captura enzimática de una timina extrahelical en la búsqueda de uracil en el ADN

Jared B Parker1, Mario A Bianchet, Daniel J Krosky

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins Medical School, 725 North Wolfe Street, Baltimore, Maryland 21205, USA.

Nature
|August 21, 2007
PubMed
Resumen

La glicosilasa de ADN de uracilo (UNG) encuentra uracilo en el ADN mediante la detección de aberturas de pares de bases, no la acción de la enzima. Este mecanismo de dinámica de pares de bases es crucial para la reparación del ADN y la prevención de mutaciones.

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