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Introduction to Membrane Traffic

The ER, Golgi apparatus, endosomes, and lysosomes work in tandem to modify, sort, and package proteins and lipids. An integrated membrane trafficking network facilitates the back and forth shuttling of molecules within different organelles in the same cell or across the cell membrane.
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Membrane lipids such as phosphatidylinositol (PI) are precursors for several membrane-bound and soluble second messengers. Specific kinases phosphorylate PI and produce phosphorylated inositol phospholipids. One such inositol phospholipids are the  phosphatidylinositol-4,5 bisphosphate [PI(4,5)P2], present in the inner half of the lipid bilayer. Upon ligand binding, GPCR stimulates Gq proteins to turn on phospholipase Cꞵ. Activated phospholipase Cꞵ cleaves PI(4,5)P2 and produces two-second...
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Video Experimental Relacionado

Updated: Jun 22, 2026

Methods to Test Visual Attention Online
09:44

Methods to Test Visual Attention Online

Published on: February 19, 2015

Acceso a Internet Acceso a Internet es el acceso a Internet.

R L Meier, R Standish

    Science (New York, N.Y.)
    |April 19, 1996
    PubMed
    Resumen

    No abstract available in PubMed .

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