Videos de Conceptos Relacionados
01:43Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
01:43Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
01:44Termination of Translation
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
01:44Termination of Translation
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
01:31Proofreading
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Errors During Replication are Corrected by the DNA Polymerase Enzyme
01:15Variance
The deviations show how spread out the data are about the mean. A positive deviation occurs when the data value exceeds the mean, whereas a negative deviation occurs when the data value is less than the mean. If the deviations are added, the sum is always zero. So one cannot simply add the deviations to get the data spread. By squaring the deviations, the numbers are made positive; thus, their sum will also be positive.The standard deviation measures the spread in the same units as the data.
También podría leer
Artículos Relacionados
Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.
Ordenar por
Same journal
Erratum for the Research Article "Awake Hippocampal Sharp-Wave Ripples Support Spatial Memory".
Science (New York, N.Y.)·2026
Same journal
Erratum for the Research Article "Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells" by Z. Zhou <i>et al</i>.
Science (New York, N.Y.)·2026
Video Experimental Relacionado
Updated: Jul 6, 2026
12:02
Molecular Evolution of the Tre Recombinase
Published on: May 29, 2008
Fue Erratum Erratum.
Science (New York, N.Y.)
|February 8, 1991
Resumen
Las toxinas naturales como el arsénico y el radón, que a menudo se encuentran en altos niveles, fueron históricamente pasadas por alto. Los esfuerzos de investigación se centraron en los residuos de contaminantes industriales, dejando de lado los importantes carcinógenos naturales.
Área de la Ciencia:
- Ciencias ambientales Ciencias ambientales.
- Toxicología Toxicología.
- Salud Pública La salud pública.
Sus antecedentes:
- Las preocupaciones con respecto a los contaminantes industriales a menudo eclipsan las toxinas de origen natural.
- Se han identificado altos niveles de arsénico natural en el agua y radón en el aire interior en varios lugares.
- Los esfuerzos de investigación históricos se han centrado desproporcionadamente en los contaminantes industriales en lugar de los peligros ambientales naturales.
Objetivo del estudio:
- Para corregir y aclarar declaraciones anteriores con respecto a la importancia relativa de los contaminantes naturales frente a los industriales.
- Para resaltar la negligencia histórica de los carcinógenos naturales significativos en la investigación de salud ambiental.
- Hacer hincapié en la necesidad de un enfoque equilibrado en la evaluación de los riesgos ambientales.
Principales métodos:
- Revisión y corrección de la correspondencia científica publicada.
- Análisis de las prioridades históricas de investigación en toxicología ambiental.
- Evaluación comparativa de los factores de riesgo asociados con los contaminantes naturales e industriales.
Principales resultados:
- Identificó correcciones específicas a las cartas publicadas sobre toxinas ambientales.
- Destacó que el arsénico y el radón naturales fueron descuidados a pesar de su alta prevalencia.
- Demostró un enfoque histórico en los contaminantes industriales a niveles minúsculos.
Conclusiones:
- Las toxinas naturales como el arsénico y el radón presentan importantes riesgos ambientales para la salud.
- Se necesita una reevaluación de las prioridades de investigación para abordar los peligros ambientales naturales de alto nivel.
- La consideración equilibrada de los contaminantes naturales e industriales es crucial para las estrategias efectivas de salud pública.