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Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Variance01:15

Variance

The deviations show how spread out the data are about the mean. A positive deviation occurs when the data value exceeds the mean, whereas a negative deviation occurs when the data value is less than the mean. If the deviations are added, the sum is always zero. So one cannot simply add the deviations to get the data spread. By squaring the deviations, the numbers are made positive; thus, their sum will also be positive.The standard deviation measures the spread in the same units as the data.

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Video Experimental Relacionado

Updated: Jul 10, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

Fue Erratum Erratum.

    Science (New York, N.Y.)
    |September 12, 1986
    PubMed
    Resumen

    Este artículo corrige errores de hecho en un informe anterior sobre matemáticos y grandes descubrimientos. Aclara la afiliación de Michael Freedman y corrige varios nombres mal escritos de prominentes matemáticos.

    Área de la Ciencia:

    • Matemáticas Las matemáticas son matemáticas.
    • La Comunicación Científica es la Comunicación Científica.

    Sus antecedentes:

    • Un artículo anterior informó inexactamente la afiliación del ganador de la Medalla Fields Michael Freedman.
    • Varios nombres de matemáticos prominentes fueron mal escritos en la publicación original.

    Objetivo del estudio:

    • Para proporcionar información precisa con respecto a la posición académica de Michael Freedman.
    • Para corregir errores ortográficos de figuras clave en matemáticas mencionadas en un artículo de investigación.

    Principales métodos:

    • Verificación de afiliaciones académicas a través de registros oficiales de la universidad.
    • Cruce de referencias de nombres con bases de datos matemáticas y científicas establecidas.

    Principales resultados:

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    Molecular Evolution of the Tre Recombinase
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    • Michael Freedman es el Charles Lee Powell Profesor de Matemáticas en la Universidad de California, San Diego, no la Universidad del Sur de California.
    • Las ortografías corregidas incluyen: Fields (anteriormente Field's), Nevanlinna (anteriormente Nevalinna/Navanlinna), Kirby (anteriormente Kirky), Atiyah (anteriormente Aryiyah) y Strassen (anteriormente Strasen).

    Conclusiones:

    • La representación precisa de los logros científicos y el personal es crucial en la presentación de informes de investigación.
    • La corrección de errores fácticos y tipográficos mantiene la integridad de la comunicación científica.