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Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution
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Las septinas regulan la organización de la actina y la detención del ciclo celular a través de la acumulación nuclear

Brandon E Kremer1, Laura A Adang, Ian G Macara

  • 1Department of Microbiology, University of Virginia School of Medicine, Charlottesville, VA 22908-0577, USA.

Cell
|September 7, 2007
PubMed
Resumen

Las septinas de los mamíferos y la proteína SOCS7 regulan la polaridad celular y la respuesta al daño del ADN. La acumulación nuclear de la proteína NCK, facilitada por SOCS7, es crucial para la detención del ciclo celular después del daño del ADN.

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