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Dinámica conformacional de ARN biestable estudiada por espectroscopia de RMN con resolución en el tiempo

Boris Fürtig1, Philipp Wenter, Luc Reymond

  • 1Johann Wolfgang Goethe University, Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance, Max von Laue-Str. 7, 60438 Frankfurt, Germany.

Journal of the American Chemical Society
|December 1, 2007
PubMed
Resumen

Los investigadores estudiaron las transiciones estructurales del ARN biestable utilizando espectroscopia de RMN con resolución temporal. Revelaron el mecanismo de plegado, la cinética y la termodinámica, identificando pasos clave en los cambios conformacionales del ARN.

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