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13C-detección en bases de ARN: revelando las relaciones estructura-cambio químico

Christophe Farès1, Irene Amata, Teresa Carlomagno

  • 1Max-Planck-Institute for Biophysical Chemistry, Department of NMR-based Structural Biology, Am Fassberg 11, D-37077 Göttingen, Germany.

Journal of the American Chemical Society
|December 7, 2007
PubMed
Resumen

Este estudio introduce nuevos experimentos 2D detectados con 13C para analizar los carbonos no protonados en bases de ARN. Estos experimentos revelan perturbaciones de desplazamiento químico relacionadas con el emparejamiento de bases y el apilamiento, ayudando a la determinación de la estructura del ARN.

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