Video Experimental Relacionado
Updated: Jul 9, 2026
06:18
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Infección por el virus del chikungunya en Italia: un brote en una región templada
G Rezza1, L Nicoletti, R Angelini
1Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Lancet (London, England)
|December 7, 2007
Resumen
El virus del chikungunya (CHIKV) causó un brote inesperado en Italia. Esta enfermedad transmitida por mosquitos pone de relieve la necesidad de preparación mundial para enfermedades infecciosas.
Área de la Ciencia:
- Epidemiología La epidemiología.
- Virología Virología.
- Salud Pública La salud pública.
Sus antecedentes:
- Los brotes del virus de Chikungunya (CHIKV) se han producido en el Océano Índico y el subcontinente.
- CHIKV es transmitido por los mosquitos Aedes spp.
- Se informó de un brote en el noreste de Italia.
Objetivo del estudio:
- Investigar un brote de enfermedad febril en Italia.
- Identificar la fuente y la transmisión del agente causal.
- Implementar una vigilancia activa para el virus Chikungunya.
Principales métodos:
- Se llevó a cabo una investigación de brote y vigilancia activa.
- Casos clínicos definidos por fiebre y dolor en las articulaciones.
- Se analizaron muestras humanas y de mosquitos utilizando PCR y serología.
- Se realizó un análisis filogenético de la región CHIKV E1.
Principales resultados:
- Se confirmó el virus de Chikungunya (CHIKV) como la causa del brote.
- Se identificaron 205 casos de infección por CHIKV entre julio y septiembre de 2007.
- El análisis filogenético relacionó las cepas italianas con las cepas del Océano Índico.
- Se observó enfermedad leve en la mayoría de los casos, con una fatalidad.
Conclusiones:
- El brote de CHIKV en una zona no tropical fue inesperado.
- Hace hincapié en la necesidad de estar preparados para las enfermedades infecciosas emergentes.
- Destaca la interconexión global en la transmisión de enfermedades.
Videos de Conceptos Relacionados
01:25Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
01:28Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
01:18Yellow Fever
Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
01:23Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
01:19Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.