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Frequency-dependent Selection01:21

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.Positive Frequency-Dependent SelectionIn positive...
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In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
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Video Experimental Relacionado

Updated: Jul 8, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

La incompatibilidad genética generalizada en C. elegans se mantiene mediante el equilibrio de la selección.

Hannah S Seidel1, Matthew V Rockman, Leonid Kruglyak

  • 1Lewis-Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. hseidel@princeton.edu

Science (New York, N.Y.)
|January 12, 2008
PubMed
Resumen

Las incompatibilidades genéticas generalmente se eliminan por selección natural. Sin embargo, un estudio en Caenorhabditis elegans encontró una incompatibilidad persistente, lo que sugiere que el polimorfismo equilibrado mantiene este conflicto genético.

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Área de la Ciencia:

  • Genética evolutiva de la genética evolutiva.
  • Genética de poblaciones genética de poblaciones.
  • Biología molecular La biología molecular.

Sus antecedentes:

  • La selección natural generalmente elimina las incompatibilidades genéticas entre poblaciones que se cruzan.
  • Las incompatibilidades genéticas pueden tener un impacto negativo en la aptitud del organismo.

Objetivo del estudio:

  • Para investigar una incompatibilidad genética distribuida globalmente en Caenorhabditis elegans.
  • Para entender los mecanismos evolutivos que mantienen esta incompatibilidad a pesar de los costos de la aptitud.

Principales métodos:

  • Análisis genéticos de poblaciones de los loci zeel-1 y peel-1 vinculados.
  • Examen de la divergencia de secuencia y el desequilibrio de enlace.
  • Evaluación de las consecuencias físicas de la incompatibilidad.

Principales resultados:

  • Se identificó una incompatibilidad específica entre los alelos de zeel-1 y peel-1.
  • Los alelos incompatibles están estrechamente vinculados y se encuentran en haplotipos comunes.
  • La selección natural preserva activamente estos haplotipos, manteniendo la incompatibilidad.

Conclusiones:

  • Un polimorfismo equilibrado que involucra loci vinculados preserva una incompatibilidad genética en Caenorhabditis elegans.
  • Este polimorfismo equilibrado persiste a pesar del flujo genético y los efectos negativos de la aptitud.