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Videos de Conceptos Relacionados

Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

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Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

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Ian Wilmut (1944-2023).

Science (New York, N.Y.)·2023
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Isogenic Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes Reveal Activation of Wnt Signaling Pathways Underlying Intrinsic Cardiac Abnormalities in Rett Syndrome.

International journal of molecular sciences·2022
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Directed differentiation of periocular mesenchyme from human embryonic stem cells.

Differentiation; research in biological diversity·2017
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Amelioration of X-Linked Related Autophagy Failure in Danon Disease With DNA Methylation Inhibitor.

Circulation·2016
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Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly.

Stem cells translational medicine·2016
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Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells.

Scientific reports·2016

Video Experimental Relacionado

Updated: Jun 23, 2026

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
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Investigación con células madre en Singapur.

Alan Colman1

  • 1Singapore Stem Cell Consortium, A*STAR Institute of Medical Biology, Singapore 138648. alan.colman@imb.a-star.edu.sg

Cell
|February 26, 2008
PubMed
Resumen

Singapur está impulsando significativamente su investigación de células madre. Esta inversión estratégica es clave para el avance del sector de la ciencia biomédica de la nación y el crecimiento económico.

Área de la Ciencia:

  • Ciencias Biomédicas Ciencias Biomédicas.
  • La Medicina Regenerativa es una Medicina Regenerativa.
  • Biología de las células madre Biología de las células madre

Sus antecedentes:

  • El compromiso de Singapur con la diversificación económica.
  • La importancia estratégica del sector de las ciencias biomédicas.
  • El papel de la investigación con células madre en el avance científico.

Objetivo del estudio:

  • Para esbozar la inversión de Singapur en la investigación de células madre.
  • Para conectar esta inversión con los objetivos económicos nacionales.
  • Para resaltar la ambición de la iniciativa de ciencia biomédica de Singapur.

Principales métodos:

  • Análisis de las estrategias nacionales de inversión.
  • Revisión de las iniciativas de la ciencia biomédica.

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  • Evaluación del impacto económico de la financiación de la investigación.

    • Principales resultados:

    • Una importante asignación financiera para la investigación con células madre.
    • Integración de la investigación de células madre en planes de desarrollo económico más amplios.
    • Establecimiento de Singapur como un actor clave en las ciencias biomédicas.

    Conclusiones:

    • La inversión de Singapur significa un enfoque estratégico en la investigación de células madre.
    • La iniciativa tiene como objetivo reforzar tanto las capacidades científicas como la prosperidad económica.
    • La nación se está posicionando para el liderazgo en el campo biomédico global.