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Author Spotlight: Investigating Hepatic Adaptations and Prediabetic Progression in Liver Diseases
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Detección de glucosa hepática a través del coactivador CREB CRTC2

Renaud Dentin1, Susan Hedrick, Jianxin Xie

  • 1Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 8, 2008
PubMed
Resumen

Los altos niveles de glucosa activan la vía de biosíntesis de la hexosamina (BPH), lo que lleva a la proteína O-glucosilación. Este proceso, mediado por O-GlcNAcase, es crucial para la intolerancia a la glucosa y las complicaciones de la diabetes.

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