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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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Adición organocatalítica asimétrica conjugada a los ésteres alénicos y las cetonas

Petteri Elsner1, Luca Bernardi, Giorgio Dela Salla

  • 1Danish National Research Foundation, Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000 Aarhus C, Denmark.

Journal of the American Chemical Society
|March 18, 2008
PubMed
Resumen

Este estudio introduce reacciones organocatalíticas de adición conjugada enantioselectiva utilizando sales quirales cuaternarias de amonio. Estas reacciones producen eficientemente beta quiral, compuestos carbonílicos gamma insaturados y derivados de ácidos alfa-amino de los beta-cetoésteres cíclicos y las iminas de glicina.

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