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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Las variantes estructurales raras interrumpen múltiples genes en las vías del neurodesarrollo en la esquizofrenia

Tom Walsh1, Jon M McClellan, Shane E McCarthy

  • 1Department of Medicine, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|March 29, 2008
PubMed
Resumen

Las variantes genéticas estructurales raras contribuyen al riesgo de esquizofrenia. Estas mutaciones impactan las vías de desarrollo neurológico, ofreciendo nuevos conocimientos sobre el trastorno.

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