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Updated: Aug 7, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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Published on: October 25, 2016

Un gen que codifica un antígeno reconocido por los linfocitos T citolíticos en un melanoma humano

P van der Bruggen1, C Traversari, P Chomez

  • 1Ludwig Institute for Cancer Research, Brussels, Belgium.

Science (New York, N.Y.)
|December 13, 1991
PubMed
Resumen

Los investigadores identificaron un nuevo gen que codifica el antígeno MZ2-E, expresado en melanoma y otros tumores, pero no en tejidos normales. Este descubrimiento permite la inmunoterapia dirigida para pacientes con tipos específicos de HLA y expresión génica tumoral.

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