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Updated: Jul 5, 2026
12:59
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
Published on: September 26, 2013
Un tipo diferente de homeostasis inmune
Eric C Freundt1, Nicolas Bidere, Michael J Lenardo
1Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Cell
|May 6, 2008
Resumen
Los investigadores descubrieron TIPE2, una proteína que regula la muerte celular y la inflamación. Esta proteína del dominio ejector de la muerte (DED) es crucial para mantener el equilibrio en el sistema inmunológico.
Área de la Ciencia:
- Inmunología Inmunología.
- Biología celular Biología celular.
- Biología Molecular Biología Molecular
Sus antecedentes:
- Las proteínas que contienen dominios efectivos de muerte (DED) son mediadores críticos de las vías de señalización celular, particularmente las que rigen la inflamación y la muerte celular programada.
- La desregulación de estas vías está implicada en varios trastornos inmunes y condiciones inflamatorias.
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