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La IL-21 y el TGF-beta son necesarios para la diferenciación de las células T(H) 17 humanas

Li Yang1, David E Anderson, Clare Baecher-Allan

  • 1Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|May 13, 2008
PubMed
Resumen

La transformación del factor de crecimiento beta (TGF-beta) y la IL-21 diferencian de manera única las células T humanas CD4 naïves en células TH17. Estos hallazgos avanzan en la comprensión de las células T(H) 17 en enfermedades autoinmunes humanas.

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