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Updated: Jul 5, 2026

In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells
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La base estructural para la proteasa regulada y la función de chaperona de DegP

Tobias Krojer1, Justyna Sawa, Eva Schäfer

  • 1Research Institute for Molecular Pathology - IMP, Dr Bohrgasse 7, A-1030 Vienna, Austria.

Nature
|May 23, 2008
PubMed
Resumen

La proteína bacteriana de choque térmico DegP actúa como un factor de control de calidad, eliminando las proteínas mal plegadas y ayudando en la biogénesis de proteínas de membrana externa. Las proteínas mal plegadas desencadenan la DegP para formar complejos activos más grandes que empaquetan o degradan sustratos.

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