La vía de síntesis del fosfatidilinositol ((3,4,5) -trifosfato en los neutrófilos activados

L R Stephens1, K T Hughes, R F Irvine

  • 1Biochemistry Department, AFRC Institute of Animal Physiology & Genetics Research, Cambridge, UK.

Nature
|May 2, 1991
PubMed
Resumen

Los neutrófilos forman lípidos específicos de inositol, incluido el fosfatidilinositol 3-fosfato, después de la activación. Una fosfatidil-inositol-4,5) bisfosfato-3-cinasa es clave para este proceso, vinculando los agonistas a la formación de lípidos 3-fosforilados.

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