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Cambios de conformación y puertas en el filtro de selectividad de los canales de potasio

Carmen Domene1, Michael L Klein, Davide Branduardi

  • 1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QZ, UK. carmen.domene@chem.ox.ac.uk

Journal of the American Chemical Society
|July 1, 2008
PubMed
Resumen

Los estudios computacionales sobre los canales de potasio (K +) revelan una puerta física dentro del filtro de selectividad, crucial para la inactivación del tipo C. Este hallazgo explica el papel conservado de la glicina en la función del canal K+.

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