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Comentario sobre "Una vía de asimilación autotrófica de dióxido de carbono de 3-hidroxipropionato/4-hidroxibutirato
Thijs J G Ettema1, Siv G E Andersson
1Department of Molecular Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, S-752 36 Sweden. thijs.ettema@ebc.uu.se
Science (New York, N.Y.)
|July 19, 2008
Resumen
Los investigadores cuestionan el descubrimiento de una nueva vía de fijación de carbono en las arqueas. El estudio desafía el supuesto papel significativo de esta vía autotrófica en el ciclo global del carbono.
Área de la Ciencia:
- Microbiología Microbiología.
- Biogeoquímica La biogeoquímica es la bioquímica.
Sus antecedentes:
- Un estudio anterior informó de una vía de fijación autótrofa de dióxido de carbono en Archaea.
- Se sugirió que esta vía juega un papel importante en el ciclo global del carbono basado en el análisis de secuencia de los datos de muestreo del océano global.
Objetivo del estudio:
- Evaluar críticamente el papel afirmado de la vía de fijación de carbono arqueal en el ciclo global del carbono.
- Cuestionar la interpretación de los datos de secuencia con respecto a la importancia de esta vía.
Principales métodos:
- Reanálisis de los datos de secuencia existentes del estudio de muestreo del océano global.
- Enfoques bioinformáticos y genómicos comparativos para evaluar la prevalencia y la función de las vías.
Principales resultados:
- La evidencia sugiere que la vía inicialmente identificada puede no ser tan extendida o funcional como se propone.
- La contribución de esta vía arqueal específica al ciclo global del carbono es probablemente sobreestimada.
Conclusiones:
- El pretendido papel sustancial de esta vía de fijación de carbono arqueal en el ciclo global del carbono requiere una mayor validación.
- Se necesita más investigación para determinar con precisión las capacidades metabólicas de las arqueas y su impacto en los ciclos biogeoquímicos.
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