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Enfermedad estreptocócica invasiva del grupo B en adultos. Un estudio basado en la población en el área metropolitana
B Schwartz1, A Schuchat, M J Oxtoby
1Meningitis and Special Pathogens Branch, Centers for Disease Control, Atlanta, GA 30333.
JAMA
|August 28, 1991
Resumen
Las infecciones por estreptococos del grupo B (GBS) son graves en adultos, con una tasa de mortalidad del 32%. Los adultos con diabetes o cáncer enfrentan riesgos significativamente más altos, lo que pone de relieve la necesidad de estrategias de prevención.
Área de la Ciencia:
- Enfermedades infecciosas Enfermedades infecciosas.
- Epidemiología La epidemiología.
- Bacteriología Bacteriología.
Sus antecedentes:
- El estreptococo del grupo B (GBS) es un patógeno significativo conocido principalmente por las infecciones neonatales.
- Las infecciones de GBS en adultos son menos conocidas, pero pueden conducir a resultados graves.
Objetivo del estudio:
- Determinar la incidencia y las manifestaciones clínicas de las infecciones por SGB en adultos.
- Para identificar poblaciones adultas específicas con mayor riesgo de infección por GBS.
Principales métodos:
- Se realizó un estudio de vigilancia retrospectivo basado en la población.
- Los datos se recopilaron de los registros de microbiología y las cartas médicas de los pacientes en el área metropolitana de Atlanta de 1982-1983.
Principales resultados:
- La incidencia anual de GBS en adultos fue de 2,4 por cada 100.000, aumentando con la edad y más alta en individuos negros.
- La tasa de mortalidad de los casos fue del 32%, con presentaciones comunes que incluyen infecciones de la piel / tejidos blandos y bacteriemia.
- Las personas con diabetes (riesgo 10,5 veces mayor) y cáncer (riesgo 16,4 veces mayor) eran significativamente más susceptibles.
Conclusiones:
- El SGB causa enfermedades graves en adultos, similares a las de los recién nacidos, lo que subraya la necesidad de desarrollar vacunas.
- Comprender la incidencia del SGB en adultos y los factores de riesgo es crucial para los esfuerzos de prevención dirigidos.
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