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How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
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Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
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The cell cycle is an organized set of events that leads the cell to divide into two daughter cells, each containing chromosomes identical to the parent cell. It is the cell cycle that leads to the formation of an entire organism from a single-cell zygote. Besides, cell division also functions in the renewal or repair of tissues in adult multicellular eukaryotes. For example, in the bone marrow, the stem cells divide to form new blood cells. Although essential for several functions, cell...
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Mitotic cell division results in daughter cells that exactly resemble the parent cell. However, errors in the DNA replication or distribution of genetic material may lead to genetic mutations that may be passed down to every new cell formed from the resulting abnormal cell. Propagation of such mutant cells is restricted through checkpoint mechanisms present at different stages of the cell cycle. These checkpoints involve regulator molecules that either promote or demote cell cycle events.
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Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
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M cyclin...
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The stepwise destruction of specific proteins is necessary for the progression and completion of the cell cycle. Such proteins are ubiquitinated by ubiquitin ligases and then subsequently destroyed by the proteasome. The SCF (Skp1/Cullin/F-box) and the anaphase-promoting complex (APC) are two important ubiquitin ligases involved in cell cycle progression. While SCF is active throughout the cell cycle, APC gets activated during metaphase to anaphase transition. Cdc20 or Cdh1 binds to APC and...
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Video Experimental Relacionado

Updated: May 1, 2026

Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations
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La búsqueda de la ciclina.

Peter K Jackson1

  • 1Genentech, Inc., Department of Cell Regulation, South San Francisco, CA 94080, USA. pjackson@gene.com

Cell
|July 30, 2008
PubMed
Resumen
Este resumen es generado por máquina.

La ciclina, una proteína clave descubierta hace 25 años, regula la división celular mediante la activación de las cinasas dependientes de la ciclina, impulsando la entrada en la mitosis. Este descubrimiento fundamental continúa impactando la investigación del ciclo celular.

Área de la Ciencia:

  • Biología Molecular Biología Molecular
  • Biología celular Biología celular.
  • La bioquímica es la bioquímica.

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Sus antecedentes:

  • El descubrimiento de la ciclina por Tim Hunt hace 25 años marcó un hito significativo en la comprensión de la regulación del ciclo celular.
  • Las ciclinas son proteínas reguladoras cruciales que controlan la progresión del ciclo celular.
  • Su oscilación es fundamental para el tiempo preciso de la división celular.