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Updated: Jul 2, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Las trans-enoil reductasas poliinsaturadas parecidas a ácidos grasos utilizadas en la biosíntesis de policetida

Stefanie B Bumpus1, Nathan A Magarvey, Neil L Kelleher

  • 1Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|August 13, 2008
PubMed
Resumen

Los investigadores identificaron PksE, una enoil reductasa de acción trans, esencial para la síntesis del enlace saturado en el dihidrobacillaeno de Bacillus subtilis. Este hallazgo revela una nueva vía de reducción de enoil en la biosíntesis de policeturo, que potencialmente la vincula con la maquinaria de los ácidos grasos poliinsaturados.

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