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Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein
11:23

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein

Published on: June 30, 2019

Cemosensores centrados en el dominio de reconocimiento: reportes versátiles y eficientes de la actividad de la

Elvedin Luković1, Juan A González-Vera, Barbara Imperiali

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|September 2, 2008
PubMed
Resumen

Una nueva estrategia enfocada en el dominio de reconocimiento (RDF, por sus siglas en inglés) mejora los ensayos de actividad de la quinasa utilizando nuevas sondas C-Sox. Estas sondas ofrecen una mayor selectividad y eficiencia para la detección de varias serina/treonina y tirosina quinasas, superando las limitaciones de diseños anteriores.

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