Video Experimental Relacionado

Updated: Jun 29, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
10:31

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability

Published on: February 3, 2022

La isomerización en los cromóforos de proteínas fluorescentes implica adición/eliminación

Jian Dong1, Fardokht Abulwerdi, Anthony Baldridge

  • 1School of Chemistry and Biochemistry, 901 Atlantic Drive; Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.

Journal of the American Chemical Society
|October 2, 2008
PubMed
Resumen

La reversión térmica del cromóforo de la proteína fluorescente verde (GFP) es sorprendentemente rápida debido a un nuevo mecanismo de adición/eliminación nucleofílico, no solo a la baja energía de activación. Este hallazgo impacta la comprensión de la función de la proteína fluorescente y el parpadeo.

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