Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Redox Reactions01:24

Redox Reactions

Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
Redox Reactions01:27

Redox Reactions

Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
Peroxisomes01:24

Peroxisomes

Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...
Redox Equilibria: Overview01:23

Redox Equilibria: Overview

A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
Oxidation and Reduction of Organic Molecules01:19

Oxidation and Reduction of Organic Molecules

Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

A NIR-IIb-excited capsule endoscope enabling high-contrast fluorescence imaging via spectrally-isolated detection for early-stage gastrointestinal cancer.

Journal of nanobiotechnology·2026
Same author

Clinical value of MRI in central lymphatic vessel evaluation and grading in primary lower-extremity lymphedema.

Vascular medicine (London, England)·2026
Same author

Photocatalytic Sulfinamide Synthesis with Boronic Acids and <i>N</i>-Sulfinylamines.

The Journal of organic chemistry·2026
Same author

A Variational Multi-Scale Model for Multi-Exposure Image Fusion.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society·2026
Same author

A self-fluorescent PS-NH<sub>2</sub>-BDC@Fe<sub>2</sub>O<sub>3</sub> nanozyme-enabled dual-mode biosensing platform for ultrasensitive quantification of ochratoxin A.

Talanta·2025
Same author

Radical-Polar Crossover Enabled Photoredox 1,2-Carbosulfinylation of Alkenes with N-Sulfinyltritylamine.

Organic letters·2025

Video Experimental Relacionado

Updated: Jun 29, 2026

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
10:58

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy

Published on: August 24, 2016

El contenido desencadenado por redox se libera de los liposomas.

Winston Ong1, Yuming Yang, Angela C Cruciano

  • 1Department of Chemistry and Center for Biomodular Multiscale Systems, Louisiana State University, Baton Rouge, Louisiana 70803, USA.

Journal of the American Chemical Society
|October 10, 2008
PubMed
Resumen

Los investigadores desarrollaron nuevos liposomas de quinona-dioleoil fosfatidiletanolamina (Q-DOPE) para la administración de fármacos dirigidos. Estos liposomas liberan su carga útil en respuesta a la actividad enzimática específica, mostrando una promesa para el tratamiento de enfermedades como el cáncer.

Más Videos Relacionados

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy
12:15

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy

Published on: February 21, 2019

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

Videos de Experimentos Relacionados

Last Updated: Jun 29, 2026

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
10:58

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy

Published on: August 24, 2016

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy
12:15

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy

Published on: February 21, 2019

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

Área de la Ciencia:

  • La bioquímica es la bioquímica.
  • Ciencia de los materiales Ciencia de los materiales.
  • Nanotecnología La nanotecnología es la nanotecnología.

Sus antecedentes:

  • Los liposomas sensibles ofrecen una administración de fármacos específica del sitio mediante la liberación de cargas útiles activadas por enzimas endógenas.
  • Los sistemas de liposomas activados existentes son limitados, lo que hace necesario el desarrollo de nuevos liposomas sensibles dirigidos a diversas enzimas reguladas al alza.

Objetivo del estudio:

  • Para sintetizar y caracterizar los nuevos liposomas de quinona-dioleoil fosfatidiletanolamina (Q-DOPE) para la liberación de carga útil desencadenada.
  • Para investigar el mecanismo de liberación activado por redox de los liposomas Q-DOPE.

Principales métodos:

  • Síntesis de lípidos Q-DOPE con un interruptor redox de quinona "bloqueado con trimetilo".
  • Preparación de liposomas estables de aproximadamente 100 nm de diámetro.
  • Evaluación de la liberación de la carga útil tras la activación redox y la escisión inducida por enzimas del grupo de quinona.

Principales resultados:

  • Los liposomas Q-DOPE estables (aprox. 100 nm) fueron sintetizados con éxito.
  • La liberación completa de la carga útil se logró a través de la activación redox del grupo principal de quinona.
  • Al modificar el interruptor "bloqueado con trimetilo" se desactivó el mecanismo de liberación de la carga útil, confirmando su papel.

Conclusiones:

  • Los liposomas Q-DOPE representan una nueva clase de sistemas de administración liposomal activados.
  • Estos liposomas se activan mediante la escisión redox del grupo principal de quinona, lo que permite la liberación de carga útil específica del sitio.
  • Los liposomas Q-DOPE tienen potencial para tratar enfermedades asociadas con la sobreexpresión de la quinona reductasa, como cánceres y afecciones inflamatorias.