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Eventos cardiovasculares asociados con rofecoxib: análisis final del ensayo APPROVe

John A Baron1, Robert S Sandler, Robert S Bresalier

  • 1Departments of Medicine, and of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA.

Lancet (London, England)
|October 17, 2008
PubMed
Resumen

Rofecoxib, un inhibidor de la ciclooxigenasa-2, aumentó significativamente los eventos cardiovasculares, incluidos el ataque cardíaco y el accidente cerebrovascular. Este riesgo elevado persistió durante un año después de suspender el medicamento.

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