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La activación de mutaciones en ALK proporciona un objetivo terapéutico en el neuroblastoma

Rani E George1, Takaomi Sanda, Megan Hanna

  • 1Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|October 17, 2008
PubMed
Resumen

Se encontraron nuevas mutaciones en el gen ALK en el neuroblastoma, un cáncer infantil. Estas mutaciones de ALK hacen que los tumores sean sensibles a los inhibidores de ALK dirigidos, ofreciendo una nueva estrategia de tratamiento.

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