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Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange
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La orientación del cuerpo medio de la maquinaria ESCRT por una bobina enrollada no canónica en CEP55

Hyung Ho Lee1, Natalie Elia, Rodolfo Ghirlando

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|October 25, 2008
PubMed
Resumen

El complejo de clasificación endosómica requerido para la maquinaria de transporte (ESCRT), incluido el CEP55, es crucial para la división celular. El análisis estructural revela cómo CEP55 se une a ALIX y TSG101, aclarando su papel en la citocinesis.

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