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Updated: Jun 28, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

Una nitrososintasa unificadora involucrada en la biosíntesis del nitrosugar

Yunfeng Hu1, Ahmad Al-Mestarihi, Catherine L Grimes

  • 1Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, USA.

Journal of the American Chemical Society
|November 6, 2008
PubMed
Resumen

Los investigadores clonaron y caracterizaron dos enzimas, ORF36 y rubN8, que realizan un paso crítico de doble oxidación en la biosíntesis de importantes productos naturales como la everninomicina y la rubradirina.

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