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Updated: Jun 28, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
07:50

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

Reacción de Mannich reductiva asimétrica a las ketiminas catalizadas por un complejo Cu (I)

Yao Du1, Li-Wen Xu, Yohei Shimizu

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.

Journal of the American Chemical Society
|November 13, 2008
PubMed
Resumen

Un nuevo método catalítico permite la síntesis estereoselectiva de valiosos derivados de aminoácidos de las ketiminas. Este acoplamiento reductivo de Mannich ofrece una ruta versátil a bloques de construcción quirales complejos para productos farmacéuticos.

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