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Neutron Crystallography Data Collection and Processing for Modelling Hydrogen Atoms in Protein Structures
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Caracterización de CalE10, la N-oxidasa involucrada en la formación de caliqueamicina hidroxiaminosugar

Heather D Johnson1, Jon S Thorson

  • 1Division of Pharmaceutical Sciences and University of Wisconsin National Drug Discovery Group, University of WisconsinMadison, Madison, Wisconsin 53706, USA.

Journal of the American Chemical Society
|December 6, 2008
PubMed
Resumen

Este estudio caracteriza a CalE10, la primera N-oxidasa del azúcar, crucial para la formación de glucósidos de caliqueamicina hidroxilamino. Confirma que la oxidación se produce en la etapa de nucleótido de azúcar, que precede a la transferencia de glucosilo.

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