Video Experimental Relacionado

Updated: Jun 26, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

Reacción directa de acoplamiento cruzado de alquenos simples con acrilatos catalizados por el catalizador de paladio

Yun-He Xu¹, Jun Lu, Teck-Peng Loh

¹Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

Journal of the American Chemical Society

|January 10, 2009

Resumen

Un nuevo método catalizado por el paladio acopla eficientemente olefinas y acrilatos. Esta reacción produce valiosos dienoatos en rendimientos moderados a buenos, avanzando la síntesis orgánica.

Área de la Ciencia:

Química orgánica es la química orgánica.
La catálisis es la catálisis.

Sus antecedentes:

La catálisis del paladio es crucial para varias transformaciones orgánicas.
Desarrollar reacciones eficientes de acoplamiento cruzado es esencial para sintetizar moléculas complejas.

Objetivo del estudio:

Desarrollar una metodología eficiente para el acoplamiento cruzado oxidativo de olefinas con acrilados.
Para sintetizar dienoatos mediante la catálisis del paladio (II).

Principales métodos:

Reacción de acoplamiento cruzado oxidativo.
El paládio (II) catalizador. catalizador.
Reacción de las olefinas con los acrilados.

Principales resultados:

Se desarrolló con éxito una metodología eficiente.
Los dienoatos se obtuvieron en rendimientos de moderados a buenos.

Conclusiones:

El método desarrollado proporciona una ruta eficiente a dienoates.
Esta reacción catalizada por el paladio ofrece una herramienta valiosa para la síntesis orgánica.

Más Videos Relacionados

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols

Published on: April 4, 2014

Videos de Conceptos Relacionados

Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

The radical dimerization of ketones or aldehydes gives vicinal diols through a pinacol coupling reaction. However, the behavior of titanium metals used for the reaction as a source of electrons is unusual. When the reaction is carried out in the presence of titanium, diols can be isolated at low temperatures. Else titanium further reacts with diols, forming alkenes through the McMurry reaction.

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Introduction
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.

Crossed Aldol Reactions: Overview

Crossed Aldol Reactions: Overview

Crossed aldol addition is the reaction between two different carbonyl compounds under acidic or basic conditions. Here, both the carbonyl compounds function as nucleophiles and electrophiles. As shown in Figure 1, such a reaction yields a mixture of products, two of which are formed via self-condensation, while the remaining two are formed via crossed-condensation. Without adjustment, the reaction's usefulness in organic chemistry is decreased.

Preparation of Alkynes: Alkylation Reaction

Preparation of Alkynes: Alkylation Reaction

Introduction
Alkylation of terminal alkynes with primary alkyl halides in the presence of a strong base like sodium amide is one of the common methods for the synthesis of longer carbon-chain alkynes. For example, treatment of 1-propyne with sodium amide followed by reaction with ethyl bromide yields 2-pentyne.

Crossed Aldol Reaction Using Strong Bases: Directed Aldol Reaction

Crossed Aldol Reaction Using Strong Bases: Directed Aldol Reaction

The reaction between two different carbonyl compounds comprising α hydrogen in the presence of a strong base like lithium diisopropylamide (LDA) to form a crossed aldol product is known as a directed aldol reaction. The directed aldol reaction is depicted in Figure 1.

Vicinal Diols via Reductive Coupling of Aldehydes or Ketones: Pinacol Coupling Overview

Vicinal Diols via Reductive Coupling of Aldehydes or Ketones: Pinacol Coupling Overview

Wilhelm Rudolph Fittig discovered the pinacol coupling reaction in 1859. It is a radical dimerization reaction and involves the reductive coupling of aldehydes or ketones in the presence of hydrocarbon solvent to yield vicinal diols.