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Función ventricular izquierda y capacidad de ejercicio.

Jasmine Grewal1, Robert B McCully, Garvan C Kane

  • 1Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

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|January 22, 2009
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Resumen
Este resumen es generado por máquina.

La disfunción diastólica ventricular izquierda reduce significativamente la capacidad de ejercicio, independientemente de la función sistólica. Esta asociación es más pronunciada con la edad avanzada y en las mujeres, destacando la función diastólica.

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Área de la Ciencia:

  • Cardiología Cardiología.
  • La ecocardiografía es una ecocardiografía.
  • Fisiología del ejercicio Fisiología del ejercicio

Sus antecedentes:

  • Existen datos limitados sobre el valor predictivo de la función ventricular izquierda para la capacidad de ejercicio.
  • Investigar las diferencias relacionadas con la edad y el sexo en esta relación es crucial.

Objetivo del estudio:

  • Para evaluar el impacto de la función cardíaca determinada por ecocardiografía en la capacidad de ejercicio.
  • Para determinar si el sexo y la edad modifican estas asociaciones.

Principales métodos:

  • Estudio transversal de 2867 pacientes sometidos a ecocardiografía por ejercicio (protocolo Bruce).
  • Se evaluó la función sistólica y diastólica del ventrículo izquierdo utilizando técnicas 2D y Doppler.
  • Se excluyeron pacientes con isquemia, fracción de eyección baja o enfermedad valvular significativa.

Principales resultados:

  • La disfunción diastólica está fuertemente e inversamente correlacionada con la capacidad de ejercicio (MET).
  • Disfunción diastólica moderada/severa reducción de la capacidad en -1,30 METs; disfunción leve en -0,70 METs.
  • Las variaciones normales de la función sistólica no afectaron la capacidad; las elevadas presiones de llenado (E/e' ≥ 15) redujeron la capacidad en -0,41 METs.
  • La edad, el sexo femenino y la obesidad (IMC > 30) fueron predictores negativos independientes de la capacidad de ejercicio.

Conclusiones:

  • La disfunción diastólica ventricular izquierda es un predictor independiente de la reducción de la capacidad de ejercicio en pacientes sin isquemia.
  • Los hallazgos enfatizan la importancia de la evaluación de la función diastólica en la evaluación de la capacidad de ejercicio.